To maintain Mayo Noble Dissecting Scissors for long-term use, sterilize them after each use using autoclaving to ensure hygiene. Regularly sharpen the blades and lubricate the pivot joint with surgical-grade oil to keep the scissors smooth and durable. Store them in a dry place, avoid cutting hard materials, and inspect them routinely for wear to preserve precision and extend their lifespan. These simple steps protect the sharpness and functionality of the instrument for years of reliable performance.